A 60-year-old woman presents to the gynecology clinic with abdominal distension and discomfort. She has a history of mucinous tumors and recent imaging shows extensive mucinous ascites. Further investigation reveals a gelatinous material filling her peritoneal cavity. The clinical team suspects pseudomyxoma peritonei and proceeds with additional diagnostic procedures to identify the primary source of the mucin.
Pseudomyxoma Peritonei is most commonly associated with which of the following conditions?
A. Thecoma ovary
B. Mucin secreting ovarian tumor
C. Carcinoid appendix
D. Mesothelioma
Answer:
The Correct Answer is: B. Mucin secreting ovarian tumor
Explanation:
Mucin secreting ovarian tumor (B):
– Pseudomyxoma peritonei (PMP) is a clinical condition characterized by the presence of mucinous ascites and mucin-secreting tumors, which primarily arise from the appendix but can also be associated with mucinous tumors of the ovary.
– The condition involves the accumulation of gelatinous material in the peritoneal cavity, often resulting in abdominal distension and discomfort.
– The primary source of PMP is usually a ruptured mucinous tumor, leading to the spread of mucin-producing cells throughout the peritoneal cavity.
Explanation of Incorrect Options:
Thecoma ovary (A):
– Thecomas are benign ovarian tumors composed of theca cells and are not associated with mucin production or pseudomyxoma peritonei.
Carcinoid appendix (C):
– Carcinoid tumors of the appendix are neuroendocrine tumors that do not typically produce mucin or lead to pseudomyxoma peritonei.
Mesothelioma (D):
– Mesothelioma is a malignant tumor of the mesothelial cells lining the pleura, peritoneum, or pericardium. It is not associated with mucin production or pseudomyxoma peritonei.
In conclusion, pseudomyxoma peritonei is most commonly associated with mucin-secreting ovarian tumors, making option B the correct answer.