Medicine MCQ 21

A 40-year-old patient has been experiencing right-sided hemicranial headaches for the past 15 years, with the pain consistently on the right side of the head. Occasionally, they also report visual symptoms during these headaches. What is the most likely diagnosis?

A. Migraine
B. Tension headaches
C. Cluster headaches
D. Intracranial vascular malformation
E. Brain tumor


Correct Answer: A. Migraine


Explanation:

The most likely diagnosis in this case is migraine. The patient’s chronic, unilateral headache and the occasional presence of visual symptoms (aura) strongly suggest migraine headaches.


Key Features Supporting Migraine:

  1. Unilateral Hemicranial Headache:
    • Migraines are typically characterized by unilateral pain, often located on one side of the head, and can persist for hours to days. In this case, the patient experiences a right-sided hemicranial headache for 15 years, which fits well with the typical course of migraine headaches.
  2. Visual Symptoms (Aura):
    • The occurrence of visual disturbances, such as seeing flashing lights or blind spots, is a classic feature of migraine aura. A visual aura occurs in about 25% of migraine sufferers and typically precedes the headache. This patient’s history of visual symptoms supports the migraine diagnosis.
  3. Chronic and Recurrent Pattern:
    • The fact that the headaches have been chronic (lasting for years) and recurrent (appearing repeatedly in the same location) fits well with the typical course of episodic migraines.

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Why Other Options Are Less Likely:

B. Tension headaches:

  • Tension headaches are usually characterized by bilateral pain, a dull and pressure-like quality, and are typically not associated with visual symptoms. The fact that the headaches are unilateral and have visual symptoms makes tension headaches less likely.

C. Cluster headaches:

  • Cluster headaches typically present as excruciating, unilateral pain often located around the eye or temple. However, they are usually associated with autonomic symptoms such as lacrimation, nasal congestion, and ptosis. Cluster headaches also tend to occur in periodic clusters, not over a chronic, continuous 15-year period.

D. Intracranial vascular malformation:

  • A vascular malformation would likely present with more acute, focal neurological symptoms, such as seizures, focal deficits, or signs of increased intracranial pressure (e.g., vomiting, altered consciousness). The patient’s history of chronic headaches with visual symptoms makes an intracranial vascular malformation less likely.

E. Brain tumor:

  • Brain tumors often present with progressive headache that may change in nature, accompanied by neurological deficits such as weakness, sensory changes, or seizures. The patient does not report any such symptoms, and the headaches have been stable for 15 years, which makes a tumor less likely.

Next Steps in Management and Investigation:

  1. Diagnosis Confirmation:
    • The diagnosis of migraine is largely clinical, based on the patient’s history and symptom pattern. However, it may be helpful to rule out other causes through neuroimaging if the clinical history is unclear or if there are red flag symptoms (e.g., sudden change in headache pattern, neurological deficits, or significant increase in frequency/intensity of headaches).
  2. Management:
    • Acute treatment of migraines usually involves triptans (e.g., sumatriptan) for symptomatic relief during an attack. NSAIDs (e.g., ibuprofen) may also be used for milder cases.
    • Preventive treatments include beta-blockers (e.g., propranolol), antiepileptics (e.g., topiramate), or TCAs (e.g., amitriptyline) for patients with frequent migraines.
  3. Lifestyle Modifications:
    • Migraine triggers should be identified and managed, such as avoiding stress, lack of sleep, or certain foods.
    • Regular sleep and a healthy diet can help prevent migraines from becoming chronic.

Conclusion:

The patient’s presentation of right-sided hemicranial headaches, visual symptoms, and a long-standing history is most consistent with migraine. The unilateral nature and the aura symptoms (visual disturbances) strongly point toward this diagnosis. Migraine treatment focuses on acute symptom relief and preventive therapy to manage frequent or severe attacks.

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